Why the study?
Does an enterovirus group-specific anti-VP1 monoclonal antibody accurately identify enteroviruses in cell culture compared to PCR and seroneutralization?
Population
Cultured cells infected by various serotypes of enterovirus and 61 strains recovered from clinical specimens…
Comparison
Enterovirus group-specific anti-VP1 monoclonal… vs Seroneutralization with intersecting pools of…
Design
Preclinical
Authors
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Should not yet change enterovirus identification practice; leaves open clinical validation of MAb beyond animal models.
Does an enterovirus group-specific anti-VP1 monoclonal antibody accurately identify enteroviruses in cell culture compared to PCR and seroneutralization?
The monoclonal antibody 5-D8/1 is a useful and accurate tool for the rapid identification of enteroviruses in cell culture, showing total agreement with PCR.
Trabelsi et al. (1995) studied this question.
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