Why the study?
Does indirect immunofluorescence assay (IFA) accurately identify serotypes of enterovirus isolates compared to neutralization assay?
Population
291 isolates of enteroviruses (95 polioviruses and 196 nonpoliovirus enteroviruses)
Comparison
Indirect immunofluorescence assay using… vs Neutralization assay
Design
Other
Authors
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May support IFA as rapid preliminary enterovirus serotyping in labs; leaves open prospective validation against neutralization before routine use.
Does indirect immunofluorescence assay (IFA) accurately identify serotypes of enterovirus isolates compared to neutralization assay?
IFA can serve as a rapid preliminary test for serotype identification of enteroviruses, with high specificity especially for polioviruses.
Rigonan et al. (1998) studied this question.
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