Key result
The periaqueductal gray plays a critical role in respiratory control and the perception of breathlessness, with dissociable activity in its sub-structures during perception and anticipation.
Why the study?
Recent evidence indicates the periaqueductal gray plays a role in breathing and breathlessness perception, but how this translates to diseases dominated by breathlessness remains to be established.
Design
Review
Authors
Loading...
May identify PAG targets for chronic breathlessness; leaves open clinical translation pending interventional trials.
Understanding the sub-structures of the PAG and their interaction with interoceptive brain networks may reveal treatment targets for chronic breathlessness.
Faull et al. (2019) conducted a review in Breathlessness. Periaqueductal gray (PAG) function was evaluated. The periaqueductal gray plays a critical role in respiratory control and the perception of breathlessness, with dissociable activity in its sub-structures during perception and anticipation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: