Key result
In patients with type 2 diabetes, a disease duration of 7.5 years or longer was strongly associated with the development of cardiac autonomic neuropathy (OR 10.63).
Why the study?
Cardiovascular autonomic neuropathy is an underdiagnosed complication of type 2 diabetes and an independent risk factor for cardiovascular mortality and events, prompting evaluation of autonomic activity and associated risk factors.
Cross-Sectional (n=242)
Yes
Odds Ratio: 10.63 (95% CI 2.56–44.06)
p-value: p=0.001
In patients with type 2 diabetes, poorer glycemic control and longer disease duration are strongly associated with a higher prevalence and severity of cardiovascular autonomic neuropathy.
Authors
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May support targeted cardiac autonomic neuropathy screening after 7.5 years of type 2 diabetes; leaves open causality and prevention effects.
Dhumad et al. (2021) conducted a cross-sectional in Type 2 Diabetes Mellitus and Cardiac Autonomic Neuropathy (n=242). Diabetes duration ≥ 7.5 years vs. Diabetes duration < 7.5 years was evaluated on Development of cardiac autonomic neuropathy (CAN) (OR 10.63, 95% CI 2.56-44.06, p=0.001). In patients with type 2 diabetes, a disease duration of 7.5 years or longer was strongly associated with the development of cardiac autonomic neuropathy (OR 10.63).
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