Key result
In children with congenital long QT syndrome, exposure to volatile general anesthesia resulted in a 2.6% incidence of perioperative adverse events related to arrhythmias.
Why the study?
What is the incidence and what are the risk factors for perioperative arrhythmic adverse events in children with congenital LQTS undergoing general anesthesia?
Population
76 children with congenital long QT syndrome undergoing general anesthesia for noncardiac surgery or device…
Design
Cohort
Follow-up
perioperative period
Authors
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Warrants heightened vigilance with volatile agents and QT-prolonging drugs in pediatric LQTS; leaves open optimal risk mitigation pending prospective studies.
Cohort (n=76)
What is the incidence and what are the risk factors for perioperative arrhythmic adverse events in children with congenital LQTS undergoing general anesthesia?
Children with congenital LQTS face a 2.6% risk of perioperative arrhythmic events under general anesthesia, particularly during emergence when exposed to QT-prolonging drugs like ondansetron and reversal agents.
Nathan et al. (2011) conducted a cohort in Congenital long QT syndrome (LQTS) (n=76). Volatile general anesthesia was evaluated on Perioperative adverse events (AEs) related to arrhythmias. In children with congenital long QT syndrome, exposure to volatile general anesthesia resulted in a 2.6% incidence of perioperative adverse events related to arrhythmias.
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