Key result
High-load resistance training combined with aerobic training significantly improved maximal aerobic capacity compared with aerobic training alone (adjusted mean difference +3.19 mL/kg/min, P=0.008).
Why the study?
It remained unknown whether high-load resistance training is superior to low-load resistance training in addition to aerobic training in patients with coronary artery disease.
Does high-load resistance training combined with aerobic training improve maximal aerobic capacity and muscle strength compared to low-load resistance training or aerobic training alone in patients with coronary artery disease?
Comparison
HL-RT plus AT vs LL-RT plus AT vs AT alone
Design
Cluster-randomized controlled clinical trial
Follow-up
36 training sessions
Authors
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Supports adding high-load resistance to aerobic training for greater fitness gains; extends RCT evidence for combined exercise in preventive cardiology.
RCT (n=79)
cluster randomized
Does high-load resistance training combined with aerobic training improve maximal aerobic capacity and muscle strength compared to low-load resistance training or aerobic training alone in patients with coronary artery disease?
Mean Difference: 3.19
p-value: p=0.008
High-load resistance training added to standard aerobic training safely improves maximal aerobic capacity and muscle strength in patients with coronary artery disease undergoing cardiac rehabilitation.
Kambič et al. (2022) conducted an RCT in coronary artery disease (n=79). High-load resistance training (HL-RT) combined with aerobic training (AT) vs. Low-load resistance training (LL-RT) combined with AT, or AT alone was evaluated on maximal aerobic capacity (VO2max) (MD +3.19 mL/kg/min, p=0.008). High-load resistance training combined with aerobic training significantly improved maximal aerobic capacity compared with aerobic training alone (adjusted mean difference +3.19 mL/kg/min, P=0.008).
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