Key result
Migraine with aura was associated with significantly higher right and left cardio-ankle vascular index values compared to healthy controls (6.5 vs 6.1, P=0.043 and 6.6 vs 6.1, P=0.009).
Why the study?
Patients with migraine with aura are at increased risk of cardiovascular disease, but data on arterial stiffness in these patients are limited.
Does migraine with aura increase arterial stiffness as measured by the cardio-ankle vascular index compared to healthy controls?
Case-Control (n=100)
Does migraine with aura increase arterial stiffness as measured by the cardio-ankle vascular index compared to healthy controls?
Migraine with aura is associated with increased arterial stiffness as measured by the cardio-ankle vascular index, suggesting a potential mechanism for the increased cardiovascular risk observed in these patients.
May inform vascular risk assessment in migraine with aura; leaves open whether stiffness drives excess CVD events.
Patients with migraine with aura are at an increased risk of cardiovascular disease. There are limited data on arterial stiffness in migraine patients with aura. The present study evaluated arterial stiffness in these patients using the cardio-ankle vascular index (CAVI). This prospective study included 50 patients with migraine with aura (43 female, mean age 38.9 ± 9.9 years). The patient group was matched for age and gender with 50 healthy individuals with no history of migraine (43 female, mean age 39.3 ± 10.3 years). All patients and control subjects underwent a comprehensive clinical evaluation by an experienced neurologist and were interviewed about their headache histories. There was no significant difference in baseline demographic characteristics and echocardiographic parameters between migraine with aura patients and the control group. Both right and left CAVI values were significantly higher in the patients with migraine with aura (6.5 ± 1.2 vs 6.1 ± 0.7, P = .043 and 6.6 ± 1.2 vs 6.1 ± 0.7, P = .009, respectively). Arterial stiffness is an important mediator of cardiovascular diseases. We found that CAVI, a novel marker of the arterial stiffness, is increased in patients with migraine with aura.
No takes yet. Share an insight, caveat, or question.
Can et al. (2024) conducted a case-control in Migraine with aura (n=100). Migraine with aura vs. Healthy individuals with no history of migraine was evaluated on Right cardio-ankle vascular index (CAVI) (p=0.043). Migraine with aura was associated with significantly higher right and left cardio-ankle vascular index values compared to healthy controls (6.5 vs 6.1, P=0.043 and 6.6 vs 6.1, P=0.009).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: