Key result
Migraine with aura linked to ~612% greater odds of diffuse carotid thickening vs non-migraineurs.
Why the study?
Migraine increases the risk of cardiovascular events, but its relationship with vascular dysfunction is unclear.
Is migraine associated with markers of carotid atherosclerosis in middle-aged women?
Cross-Sectional (n=277)
Is migraine associated with markers of carotid atherosclerosis in middle-aged women?
Odds Ratio: 7.12 (95% CI 1.05–48.49)
Absolute Event Rate: 6.8% vs 1.3%
In middle-aged women, migraine with aura is associated with increased carotid thickening, whereas migraine without aura is associated with a lower risk of carotid plaques and arterial stiffening.
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Migraine may associate with carotid markers in women without CVD; hypothesis-generating and requires prospective confirmation before clinical relevance.
Magalhães et al. (2018) conducted a cross-sectional in Migraine (n=277). Migraine vs. Non-migraineurs was evaluated on Diffuse carotid thickening (OR 7.12, 95% CI 1.05-48.49). Migraine with aura was associated with an increased risk of diffuse carotid thickening compared to non-migraineurs (6.8% vs 1.3%; OR 7.12, 95% CI 1.05-48.49).
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