Key result
Ectopic lipid storage in tissues such as skeletal muscle, liver, myocardium, and pancreas is associated with insulin resistance, inflammatory processes, and organ dysfunction.
Ectopic lipid accumulation in non-adipose tissues, including the myocardium, is linked to metabolic and contractile dysfunction, highlighting its potential role in the pathogenesis of heart failure and insulin resistance.
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Ectopic lipid may drive cardiometabolic organ dysfunction; leaves open causal confirmation and targeted interventions.
Szendroedi et al. (2008) conducted a review in Ectopic lipid storage and organ dysfunction. Ectopic lipid storage was evaluated. Ectopic lipid storage in tissues such as skeletal muscle, liver, myocardium, and pancreas is associated with insulin resistance, inflammatory processes, and organ dysfunction.
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