Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 4, 2014Journal of Hypertension

Noninvasive characterization of the effect of aortic impedance on left ventricular structure

View Full Paper
Ask AI
Bookmark
Share

Key result

Aortic characteristic impedance was directly associated with left ventricular mass index (r=0.19, P<0.001) and relative wall thickness (r=0.14, P<0.01) in untreated hypertensive individuals.

Population

438 untreated hypertensive individuals (and a referenced normotensive group of n=70)

Design

Editorial

Authors

MBMark ButlinMacquarie UniversityAAAlberto AvolioVascular Medicine

Discussion

Loading...

Member takes

Implication

Noninvasive estimation of aortic characteristic impedance is associated with left ventricular mass and geometry, highlighting its potential for bedside assessment of cardiovascular function despite methodological redundancies.

Structured PICO

P
Population
438 untreated hypertensive individuals assessed for the relationship between aortic characteristic impedance and left ventricular structure.
E
Exposure
Noninvasive estimation of aortic characteristic impedance using brachial transfer function (SphygmoCor) and flow estimation (ArcSolver)
O
Outcome
Association of aortic characteristic impedance with left ventricular mass and geometrysurrogate

Main Result

Effect estimate: r = 0.19

p-value: p=<0.001

Noninvasive estimation of aortic characteristic impedance is associated with left ventricular mass and geometry, highlighting its potential for bedside assessment of cardiovascular function despite methodological redundancies.

Limitations

  • The method of computing aortic characteristic impedance has an inherent redundancy, making it partly dependent on the model.
  • The association between aortic characteristic impedance and left ventricular structural parameters is relatively weak.
  • Uncertainties in the left ventricular parameter measurements.
  • Method of computing aortic characteristic impedance has an inherent redundancy because flow is derived from pressure using a model
  • Computed value of aortic characteristic impedance is highly dependent on the amplitude of aortic pressure (P1)

Cite This Study

Butlin et al. (2014) conducted an editorial in Untreated hypertension (n=438). Aortic characteristic impedance was evaluated on Left ventricular mass index (r = 0.19, p=<0.001). Aortic characteristic impedance was directly associated with left ventricular mass index (r=0.19, P<0.001) and relative wall thickness (r=0.14, P<0.01) in untreated hypertensive individuals.

synapsesocial.com/papers/6a7c9772f501f50849cf7fcdhttps://doi.org/10.1097/hjh.0000000000000389

Topics

Hypertension management
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An analysis of the relationship between central aortic and peripheral upper limb pressure waves in man1993 · 877 citations
  2. 2Why are women more likely than men to develop heart failure with preserved ejection fraction?2011 · 233 citations
  3. 3Calculation of arterial characteristic impedance: a comparison using different blood flow models2013 · 23 citations
  4. 4Input impedance of the systemic circulation in man.1977 · 295 citations
  5. 5Quantification of Wave Reflection in the Human Aorta From Pressure Alone2006 · 310 citations