Key result
Carotid augmentation index was a significant independent predictor of left ventricular diastolic function in healthy women (β = -0.257; P=0.02) but not in men.
Cross-Sectional (n=167)
Effect estimate: β = -0.257
p-value: p=0.02
The correlation between arterial stiffness (augmentation index) and left ventricular diastolic function is stronger in healthy women than in healthy men.
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Suggests possible sex differences in arterial-ventricular coupling; hypothesis-generating and requires longitudinal confirmation before clinical consideration.
Higashi et al. (2013) conducted a cross-sectional in Healthy population without significant atherosclerosis (n=167). Female sex vs. Male sex was evaluated on Correlation between carotid augmentation index (AIx) and peak early diastolic mitral annular velocity (e') (β = -0.257, p=0.02). Carotid augmentation index was a significant independent predictor of left ventricular diastolic function in healthy women (β = -0.257; P=0.02) but not in men.
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