Key result
The population-based mortality rate of acute myocardial infarction was 34% to 42%, while among patients without out-of-hospital cardiac arrest, reperfusion therapy significantly reduced in-hospital mortality compared to no reperfusion (3.4% vs 22.7%).
Observational (n=232)
Yes
Absolute Event Rate: 3.4% vs 22.7%
p-value: p=<0.0001
The population-based mortality rate of AMI remains high (34% to 42%) when including out-of-hospital cardiac arrests, highlighting the critical need for improved prehospital care.
High AMI mortality including OHCA supports prehospital care focus; leaves open causal reperfusion benefits in broader cohorts.
The in-hospital mortality rate of acute myocardial infarction (AMI) is improving. In Japan, little information exists concerning the incidence and mortality of AMI. Therefore, our population-based analysis examined the incidence and mortality rate in AMI cases in individuals that lived in the Matsumoto region in 2002. We studied 169 AMI patients who were admitted within 14 days after a non-out-of-hospital cardiac arrest (non-OHCA group) and 63 patients with an AMI-related out-of-hospital cardiac arrest (OHCA group). The in-hospital mortality rate of the non-OHCA group was 9.5% (reperfusion therapy [+] 3.4%, [-] 22.7%, P < 0.0001). The rate of return of spontaneous circulation and the survival rate were 21% and 1.6%, respectively, in the OHCA group. The incidence of AMI in the non-OHCA and OHCA groups combined was 55.2 to 63.1 events/100,000 people annually and the mean age of AMI patients was 70 ± 13 years. The population-based mortality rate of AMI was 34% to 42%. The mortality rate of AMI remains high, and most deaths occur outside of the hospital. Prehospital care may lower the mortality rate of AMI.
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Aso et al. (2011) conducted an observational in Acute myocardial infarction (n=232). Reperfusion therapy vs. No reperfusion therapy was evaluated on In-hospital mortality (p=<0.0001). The population-based mortality rate of acute myocardial infarction was 34% to 42%, while among patients without out-of-hospital cardiac arrest, reperfusion therapy significantly reduced in-hospital mortality compared to no reperfusion (3.4% vs 22.7%).
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