Why the study?
Do baseline levels of fibrinolytic factors predict the risk of myocardial infarction or sudden death in patients with angina pectoris?
Population
3043 patients with angina pectoris
Design
Cohort
Follow-up
2 years
Authors
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May aid risk stratification in angina; leaves open whether markers add to conventional models or guide therapy.
Do baseline levels of fibrinolytic factors predict the risk of myocardial infarction or sudden death in patients with angina pectoris?
The prognostic role of PAI-1 in predicting coronary events is mainly related to insulin resistance, whereas TPA antigen's role is explained by its relationship with insulin resistance, inflammation, and endothelial cell damage.
Pyke et al. (1996) studied this question.
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