Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 14, 2005StrokeOpen Access

Variation in the Carotid Bifurcation Geometry of Young Versus Older Adults

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does carotid bifurcation geometry exhibit less interindividual variation in young adults compared to older adults?

Population

50 subjects, comprising 25 young adults and a control group of 25 older subjects.

Comparison

Assessment of 3D carotid bifurcation geometry… vs Comparison between young adults and older…

Design

Cross-sectional

Authors

JTJonathan B. ThomasUniversity of FloridaLALuca AntigaUniversity of BergamoJMJaques S. MilnerRobarts Clinical Trials

Discussion

Loading...

Member takes

Implication

Less geometric variation in young carotid bifurcations may reflect aging effects; leaves open link to atherosclerosis.

Structured PICO

Does carotid bifurcation geometry exhibit less interindividual variation in young adults compared to older adults?

P
Population
50 subjects, comprising 25 young adults (mean age 24+/-4 years) and a control group of 25 older subjects (mean age 63+/-10 years).
I
Intervention
Assessment of 3D carotid bifurcation geometry using MRI.
C
Comparator
Comparison between young adults and older subjects.
O
Outcome
Interindividual variation in carotid bifurcation geometric parameters (bifurcation angle, ICA angle, CCA tortuosity, ICA tortuosity, ECA/CCA diameter ratio, ICA/CCA diameter ratio, and bifurcation area ratio).surrogate

Carotid bifurcation geometry shows significantly less interindividual variation in young adults compared to older adults, suggesting a complex relationship between vascular aging, geometry, and atherosclerosis development.

Cite This Study

Thomas et al. (2005) studied this question.

synapsesocial.com/papers/6a7ca2c580d29ce2cbfab3bbhttps://doi.org/10.1161/01.str.0000185679.62634.0a
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Geometric modeling of the carotid bifurcation in humans: Implications in ultrasonic doppler and radiologic investigations1985 · 28 citations
  2. 2Hemodynamic Shear Stress and Its Role in Atherosclerosis1999 · 3,665 citations
  3. 3Internal Carotid Artery Angle of Origin2003 · 95 citations
  4. 4Reconstruction of carotid bifurcation hemodynamics and wall thickness using computational fluid dynamics and MRI2001 · 255 citations
  5. 5Robust and Objective Decomposition and Mapping of Bifurcating Vessels2004 · 230 citations