Population
Patients with essential hypertension
Design
Review
Authors
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Hypothesis-generating for endothelial-targeted therapies in hypertensive cardiorenal disease; prospective trials required before clinical adoption.
Endothelial dysfunction may serve as a critical pathophysiological link between renal impairment and cardiovascular complications in patients with essential hypertension.
Carmine Zoccali (2006) studied this question.
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