Key result
Frail and pre-frail older patients with hypertension used significantly more antihypertensive medications (2.06 vs 1.95, p=0.003) and exhibited more comorbidities and functional decline compared to robust patients.
Why the study?
With the increasing prevalence of hypertension with age and an expanding older population, research was needed to identify the clinical characteristics of older hypertensive patients in Korea according to frailty status.
Population
2,085 older hypertensive Korean patients aged ≥ 65 years from 11 university hospitals
Comparison
Characteristics based on frailty status
Design
Screening assessment analysis from a prospective, multicenter, open-label randomized clinical trial
Authors
Loading...
Frail older hypertensives exhibit more comorbidities, functional decline, and medication use; leaves open whether frailty modifies intensive BP target benefits.
Cross-Sectional (n=2,085)
Open-label
Yes
Absolute Event Rate: 2.06% vs 1.95%
p-value: p=0.003
Choi et al. (2024) conducted a cross-sectional in Hypertension (n=2,085). Frailty and pre-frailty vs. Robust status was evaluated on Mean number of antihypertensive medications (p=0.003). Frail and pre-frail older patients with hypertension used significantly more antihypertensive medications (2.06 vs 1.95, p=0.003) and exhibited more comorbidities and functional decline compared to robust patients.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: