Key result
Experimental models of pericarditis in laboratory animals provide an opportunity to investigate the mechanisms of adhesive scar formation and explore the potential of novel anti-adhesive drugs.
Why the study?
Experimental biological test systems are needed to better understand the mechanisms of adhesive pericarditis after cardiac surgery and to develop effective prevention strategies.
Design
Review of experimental animal models
Authors
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Highlights mechanisms of adhesive pericarditis; leaves open whether targeting fibrogenesis reduces reoperative complications.
Experimental models of pericarditis in animals are essential for understanding the mechanisms of postoperative pericardial adhesions and developing new preventive anti-adhesive therapies.
E.A. et al. (2023) conducted a review in Pericarditis and pericardial adhesions. Experimental models of pericarditis in laboratory animals provide an opportunity to investigate the mechanisms of adhesive scar formation and explore the potential of novel anti-adhesive drugs.
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