Why the study?
Does daily treatment with ARBs improve blood pressure, autonomic function, and health-related quality of life in patients with hypertension?
Does daily treatment with ARBs improve blood pressure, autonomic function, and health-related quality of life in patients with hypertension?
ARB therapy in hypertensive patients is associated with improvements in blood pressure, autonomic function, and health-related quality of life over 16 weeks.
Supports ARB use for BP plus autonomic and HRQOL gains in hypertension; extends evidence beyond BP lowering alone.
The aim of the present study was to examine the relationships between the anti-hypertensive effects, autonomic function, and health-related quality of life (HRQOL) following treatment of hypertensive subjects with angiotensin receptor blockers (ARBs) in hypertensives. Nineteen patients with hypertension were assigned randomly to daily treatment with ARBs. After 16 weeks of treatment, blood pressure (BP) and 24 h the ratio of low frequency to high frequency component (LF/HF), an index of sympathovagal balance were decreased by ARBs. The HRQOL scores improved during the study. In this study, ARB therapy was associated with an improvement in BP, autonomic function, and HRQOL.
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Okano et al. (2009) studied this question.
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