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February 1, 1996Annals of Internal Medicine

Recent Age-Related Trends in the Use of Thrombolytic Therapy in Patients Who Have Had Acute Myocardial Infarction

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Why the study?

Does age affect the likelihood of receiving thrombolytic therapy in patients with acute myocardial infarction?

Population

350,755 patients who had an acute myocardial infarction from 1 July 1990 to 30 September 1994 across 1249…

Design

Cohort

Authors

JGJerry H. GurwitzHeart Failure & Transplant

Discussion

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Implication

Age disparities in thrombolytic use for MI persist after adjustment; leaves open whether this reflects appropriate caution or missed opportunities in older patients.

Structured PICO

Does age affect the likelihood of receiving thrombolytic therapy in patients with acute myocardial infarction?

P
Population
350,755 patients who had an acute myocardial infarction from 1 July 1990 to 30 September 1994 across 1249 U.S. hospitals.
I
Intervention
Thrombolytic therapy
O
Outcome
Trends in the proportions of patients who received thrombolytic therapy according to age and sex

Older patients with acute myocardial infarction are significantly less likely to receive thrombolytic therapy than younger patients, even after adjusting for eligibility criteria, although use in the elderly is increasing over time.

Cite This Study

Jerry H. Gurwitz (1996) studied this question.

synapsesocial.com/papers/6a7ca5c2f501f50849cf82a0https://doi.org/10.7326/0003-4819-124-3-199602010-00001
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Age-Related Trends (1986-1993) in the Use of Thrombolytic Agents in Patients With Acute Myocardial Infarction1997 · 34 citations
  2. 2Age-related trends (1986-1993) in the use of thrombolytic agents in patients with acute myocardial infarction. The Worcester Heart Attack Study1997 · 34 citations
  3. 3Effectiveness of Thrombolytic Therapy for Acute Myocardial Infarction in the Elderly2002 · 74 citations
  4. 4Thrombolytic Therapy for Eligible Elderly Patients With Acute Myocardial Infarction1997 · 160 citations
  5. 5Relationship of Age with Eligibility for Thrombolytic Therapy and Mortality Among Patients with Suspected Acute Myocardial Infarction1994 · 55 citations