Key result
Only 3.8% of 312 eligible patients underwent primary aldosteronism screening, with just 41.7% screened appropriately and 4 true positive results misinterpreted as negative.
Why the study?
Primary aldosteronism is underdiagnosed and the aldosterone-to-renin ratio is often misinterpreted, prompting an evaluation of appropriate screening and management rates in primary care.
Population
312 newly established adults with indications for primary aldosteronism screening in a single clinic
Design
Cohort study
Follow-up
Up to 12 months
Authors
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Suboptimal PA screening rates and ARR misinterpretation persist in clinics; leaves open whether education or protocols improve detection in resistant hypertension.
Cohort (n=312)
No
Primary aldosteronism remains significantly under-screened and mismanaged in primary care settings, highlighting a critical need for standardized protocols and provider education.
Hui et al. (2026) conducted a cohort in Indications for primary aldosteronism screening (n=312). Primary aldosteronism screening was evaluated on Rates of appropriate PA screening and management. Only 3.8% of 312 eligible patients underwent primary aldosteronism screening, with just 41.7% screened appropriately and 4 true positive results misinterpreted as negative.
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