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January 9, 2022Internal Medicine Journal

Screening for primary aldosteronism in the diabetic population: a cohort study

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Key result

Among diabetic patients who fulfilled the Endocrine Society criteria for primary aldosteronism screening, only 23.3% (14 of 60) were actually screened using the aldosterone-to-renin ratio.

Why the study?

Hypertension is common in patients with type 2 diabetes who carry increased cardiovascular risk, but it is unknown how frequently they are tested for primary aldosteronism.

Are patients with diabetes and hypertension adequately screened for primary aldosteronism according to guidelines?

Population

272 patients who attended tertiary diabetes clinics with two or more blood pressure measurements

Comparison

Patients who met primary aldosteronism screening criteria vs those who did not

Design

Retrospective cohort study

Authors

STSuzanne J. TanRLRenata LibiantoHudson Institute of Medical ResearchJYJun YangMonash University

Discussion

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Implication

PA screening rates remain low despite indications in diabetes clinics; leaves open the need for targeted implementation strategies in this population.

Study Design

Type

Cohort (n=272)

Structured PICO

Are patients with diabetes and hypertension adequately screened for primary aldosteronism according to guidelines?

P
Population
272 patients attending tertiary diabetes clinics with two or more blood pressure measurements over a 1-year period.
E
Exposure
Screening for primary aldosteronism using the aldosterone-to-renin ratio (ARR)
O
Outcome
Proportion of eligible patients screened for primary aldosteronism according to the Endocrine Society's 2016 guidelines

Only a minority of diabetic patients who fulfill criteria for primary aldosteronism screening are actually screened in tertiary care, indicating a significant gap in clinical practice.

Cite This Study

Tan et al. (2022) conducted a cohort in Type 2 diabetes (n=272). Indication for primary aldosteronism screening vs. No indication for screening was evaluated on Screening for primary aldosteronism using the aldosterone-to-renin ratio. Among diabetic patients who fulfilled the Endocrine Society criteria for primary aldosteronism screening, only 23.3% (14 of 60) were actually screened using the aldosterone-to-renin ratio.

synapsesocial.com/papers/6a93cb1017272e2ca0f2c31ehttps://doi.org/10.1111/imj.15690

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 381998 · 6,746 citations
  2. 2Prevalence of primary aldosteronism among patients with type 2 diabetes2017 · 14 citations
  3. 3Primary Aldosteronism With Type 2 Diabetes Mellitus Requires More Antihypertensive Drugs for Blood Pressure Control: A Retrospective Observational Study2018 · 5 citations
  4. 4Obesity as a Key Factor Underlying Idiopathic Hyperaldosteronism2018 · 77 citations
  5. 5The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline2016 · 2,964 citations