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July 1, 2002Alcoholism Clinical and Experimental Research

Relationship of Light to Moderate Alcohol Consumption and Risk of Hypertension in Japanese Male Office Workers

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Why the study?

Does light to moderate alcohol consumption increase the risk of incident hypertension in Japanese male office workers?

Population

3,784 hypertension-free Japanese male office workers aged 23 to 59 years selected from an initial survey of…

Comparison

Alcohol consumption vs Nondrinkers

Design

Cohort

Follow-up

4 years

Authors

NNNoriyuki NakanishiKMKae MakinoKNKazue Nishina

Discussion

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Overview

Light-to-moderate alcohol intake was associated with higher hypertension incidence in Japanese men; leaves open whether lowering intake below 12 g/day prevents cases.

Structured PICO

Does light to moderate alcohol consumption increase the risk of incident hypertension in Japanese male office workers?

P
Population
3,784 hypertension-free Japanese male office workers aged 23 to 59 years (baseline systolic BP <140 mm Hg, diastolic BP <90 mm Hg, no medication for hypertension, and no history of hypertension) selected from an initial survey of 5,275 men.
I
Intervention
Alcohol consumption (current drinkers averaging <12, 12 to 22, 23 to 45, or ≥46 g/day of ethanol)
C
Comparator
Nondrinkers
O
Outcome
Incident cases of hypertension (systolic BP ≥140 mm Hg, diastolic BP ≥90 mm Hg, or both, or receipt of antihypertensive medication) over 4 yearssurrogate

Even light to moderate alcohol consumption (≥12 g/day) significantly increases the risk of incident hypertension in middle-aged men, demonstrating a dose-dependent relationship between alcohol intake and blood pressure.

Cite This Study

Nakanishi et al. (2002) studied this question.

synapsesocial.com/papers/6a7ca98d93373eeacd190a15https://doi.org/10.1097/00000374-200207000-00008
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Relationship of Alcohol Intake With Blood Pressure in Young Adults1995 · 132 citations
  2. 2Alcohol Consumption and Blood Pressure1977 · 875 citations
  3. 3Alcohol Consumption, Drinking Pattern and Blood Pressure: Analysis of Data from the Italian National Research Council Study1987 · 78 citations
  4. 4Alcohol and blood pressure and its interaction with smoking and other behavioural variables: results from the MONICA Augsburg Survey 1984-19851991 · 71 citations
  5. 5Implications of the INTERSALT study.1991 · 291 citations