April 1, 2004Archives of Pathology & Laboratory Medicine
Diagnostic and prognostic value of cardiac troponin I assays in patients admitted with symptoms suggestive of acute coronary syndrome.
Why the study?
Does the Ortho Vitros Troponin I assay perform comparably to the Beckman Access AccuTnI assay for detecting myocardial infarction and predicting all-cause death in patients with suspected ACS?
Population
200 consecutively admitted patients presenting with symptoms suggestive of acute coronary syndrome at a…
Comparison
Ortho Vitros Troponin I assay vs Beckman Access AccuTnI assay
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports comparable Ortho Vitros and Beckman troponin accuracy for MI in suspected ACS; leaves open prospective validation before broader adoption.
Structured PICO
Does the Ortho Vitros Troponin I assay perform comparably to the Beckman Access AccuTnI assay for detecting myocardial infarction and predicting all-cause death in patients with suspected ACS?
P
Population
200 consecutively admitted patients presenting with symptoms suggestive of acute coronary syndrome (ACS) at a metropolitan medical center.
I
Intervention
Ortho Vitros Troponin I assay
C
Comparator
Beckman Access AccuTnI assay
O
Outcome
Detection of myocardial infarction and risk stratification for all-cause deathsurrogate
The Ortho Vitros and Beckman Access cTnI assays demonstrate comparable diagnostic accuracy for myocardial infarction and prognostic value for all-cause death in patients with suspected ACS.
Cite This Study
Apple et al. (2004) studied this question.