April 1, 2004Archives of Pathology & Laboratory Medicine
Diagnostic and Prognostic Value of Cardiac Troponin I Assays in Patients Admitted With Symptoms Suggestive of Acute Coronary Syndrome
Why the study?
Do the Ortho Vitros and Beckman Access cardiac troponin I assays have comparable diagnostic and prognostic value in patients with suspected acute coronary syndrome?
Population
200 consecutively admitted patients presenting with symptoms suggestive of acute coronary syndrome at a…
Comparison
Measurement of serial plasma samples using the… vs Measurement using the Beckman Access AccuTnI assay
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports assay interchangeability for MI detection in suspected ACS; extends prior comparisons but leaves generalizability open.
Structured PICO
Do the Ortho Vitros and Beckman Access cardiac troponin I assays have comparable diagnostic and prognostic value in patients with suspected acute coronary syndrome?
P
Population
200 consecutively admitted patients presenting with symptoms suggestive of acute coronary syndrome (ACS) at a metropolitan medical center over a 2-month period.
I
Intervention
Measurement of serial plasma samples using the Ortho Vitros Troponin I assay
C
Comparator
Measurement using the Beckman Access AccuTnI assay
O
Outcome
Detection of myocardial infarction and risk stratification for all-cause deathsurrogate
The Ortho Vitros and Beckman Access cardiac troponin I assays provide comparable diagnostic accuracy for myocardial infarction and prognostic value for all-cause death in patients with suspected ACS.
Cite This Study
Apple et al. (2004) studied this question.