Why the study?
Habitual vigorous resistance training may blunt cardiovagal baroreflex sensitivity through increased central arterial stiffness and decreased arterial compliance, but this effect remained to be examined.
Does habitual vigorous resistance training blunt cardiovagal baroreflex sensitivity and alter central arterial mechanical properties in healthy men?
Does habitual vigorous resistance training blunt cardiovagal baroreflex sensitivity and alter central arterial mechanical properties in healthy men?
Habitual vigorous resistance training in young men is associated with increased central arterial stiffness, decreased arterial compliance, and blunted cardiovagal baroreflex sensitivity.
Vigorous resistance training may associate with lower BRS; leaves open whether it impairs baroreflex function.
Background: Blunted cardiovagal baroreflex sensitivity (BRS) is correlated with elevation of central arterial stiffness and/or reduction of arterial compliance with aging. Resistance-trained who habitually perform vigorous resistance training (RT) may blunt cardiovagal BRS due to an increase in central arterial stiffness and a decrease in arterial compliance. Therefore, the purpose of this study was to examine the effect of vigorous RT on cardiovagal BRS in a cross-sectional study to compare resistance-trained with age-matched non-resistance-trained. Methods: This cross-sectional study included resistance-trained men (resistance-trained group: n = 20) and age-matched non-resistance-trained men (control group: n = 20). The β-stiffness index and arterial compliance were assessed at the right carotid artery, and the cardiovagal BRS was estimated by the slope of the R-R interval and systolic blood pressure during phase IV of the Valsalva maneuver. Results: The β-Stiffness index was significantly higher in the resistance-trained group than in the control group (4.4 ± 0.2 vs. 5.9 ± 0.3 a.u., P < 0.01). In contrast, the resistance-trained group had significantly lower arterial compliance and cardiovagal BRS than the control group (0.20 ± 0.01 vs. 0.15 ± 0.01 mm 2 /mmHg and 12.9 ± 1.2 vs. 9.0 ± 0.5 ms/mmHg, respectively, P < 0.01 for both measurements). Moreover, cardiovagal BRS was inversely and positively correlated with the β-stiffness index (combined: r = - 0.59, P < 0.01; control: r = - 0.56, P < 0.01; resistance-trained: r = - 0.50, P < 0.05) and arterial compliance (combined: r = 0.64; control: r = 0.61; resistance-trained: r = 0.55, all P < 0.01), respectively. Conclusion: Resistance-trained group was higher arterial stiffness and lower compliance and blunter cardiovagal BRS compared with control group. These results suggest that vigorous RT blunts cardiovagal BRS. Trial registration: University hospital Medical Information Network (UMIN) in Japan, UMIN000038116. Registered on September 27, 2019.
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Nakamura et al. (2021) studied this question.
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