What question did this study set out to answer?

To evaluate clinical features, vessel involvement, diagnostic pathways, and outcomes among patients developing acute coronary syndrome alongside COVID-19 infection.

January 30, 2023Open Access Macedonian Journal of Medical SciencesOpen Access

COVID-19-induced Acute Coronary Syndrome: A Review of 77 Cases

View Full Paper

Ask AI

Bookmark

Why the study?

SARS-CoV-2 impacts extra-respiratory organs such as the heart, but comprehension of the presentation, clinical features, diagnostic process, and outcomes of COVID-19-induced ACS required further review.

Key Points

To evaluate clinical features, vessel involvement, diagnostic pathways, and outcomes among patients developing acute coronary syndrome alongside COVID-19 infection.
Conducted a systematic search across PubMed, Web of Science, and Scopus databases.
Identified and reviewed case report studies meeting criteria for confirmed acute coronary syndrome and documented COVID-19 infection (N=77 cases).
The most common clinical presentation symptoms among patients were shortness of breath, fatigue, fever, and cough.
The right coronary artery was identified as the most frequently involved vessel among acute coronary events.
No direct causal association was demonstrated between the COVID-19 pandemic and the occurrence of acute coronary syndrome.

Structured PICO

Population

77 case reports of patients with confirmed ischemic heart disease (Acute Coronary Syndrome) and a reported diagnosis of COVID-19, 67.5% male, from different countries.

Outcome

Clinical features, diagnostic process, and outcomes of ACS cases resulting from COVID-19

This review of 77 case reports characterizes the clinical presentation of COVID-19-associated ACS, highlighting typical symptoms of chest pain and shortness of breath, frequent right coronary artery involvement, and a 23.4% mortality rate.

Limitations

Included only case reports with no evidence of relationship
High risk of information bias due to incomplete data
Possible confounding by comorbidities
Inability to determine causal relationship
Heterogeneous nature of research with some studies of moderate quality

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Alerts clinicians to ACS in COVID-19; leaves open incidence, mechanisms, and management strategies.

Cite This Study

Alharbi et al. (2023) studied this question.

synapsesocial.com/papers/6a7cb329b7ca9b673b7cd2c2 https://doi.org/10.3889/oamjms.2023.11203

View Full Paper

Ask AI

Bookmark

COVID-19-induced Acute Coronary Syndrome: A Review of 77 Cases

Key Points

Structured PICO

Limitations

Discussion

Implication

Cite This Study

COVID-19-induced Acute Coronary Syndrome: A Review of 77 Cases

Key Points

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider