Population
Patients with multiple sclerosis (MS)
Design
Review
Authors
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Early MS white matter and immune changes merit targeted studies; hypothesis-generating and should not yet alter clinical practice.
Highlights early biochemical changes and immunological abnormalities, such as increased CSF IgG and T cell defects, in the pathogenesis of multiple sclerosis.
M. L. Cuzner (1980) studied this question.
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