What question did this study set out to answer?

To evaluate the clinical, hematologic, and bone marrow characteristics alongside the underlying causes of iron deficiency in hospitalized older patients.

February 1, 1965JAMA

Clinical Aspects of Iron Deficiency

View Full Paper

Ask AI

Bookmark

Authors

CKCarol K. KasperUniversity of Southern California

Discussion

Member takes

Implication

Observational study reveals atypical hematologic indices and varied gastrointestinal bleeding sources in older patients with iron-deficiency anemia, highlighting complex diagnostic challenges.

Key Points

To evaluate the clinical, hematologic, and bone marrow characteristics alongside the underlying causes of iron deficiency in hospitalized older patients.
Evaluated 100 hospitalized older patients diagnosed with iron-deficiency anemia.
Analyzed peripheral blood parameters, red blood cell morphology, platelet counts, bone marrow erythroblast sizes, and sources of occult blood loss.
Mean corpuscular hemoglobin concentration varied with anemia severity, but 21 of 100 patients exhibited normal or elevated mean corpuscular volumes, 22 had circulating nucleated red blood cells, and platelets were frequently elevated.
Primitive bone marrow erythroblasts were smaller than normal controls, and chronic occult gastrointestinal bleeding was the predominant cause across more than 12 distinct lesion types, though 21 patients had no identifiable source.

Cite This Study

Carol K. Kasper (1965) studied this question.

synapsesocial.com/papers/6a7cb6cf3dbea9de81611927 https://doi.org/10.1001/jama.1965.03080050005001

View Full Paper

Ask AI

Bookmark

Implication

Observational study reveals atypical hematologic indices and varied gastrointestinal bleeding sources in older patients with iron-deficiency anemia, highlighting complex diagnostic challenges.

Clinical Aspects of Iron Deficiency

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical Aspects of Iron Deficiency

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider