Liver and Thyroid Monitoring in Ambulatory Patients Prescribed Amiodarone in 10 HMOs

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Population

1,055 ambulatory patients dispensed amiodarone for at least 180 days across 10 health maintenance…

Design

Cohort

Follow-up

210 days

Authors

Discussion

Amiodarone monitoring gaps persist in ambulatory practice; this Level 3 cohort analysis leaves open whether targeted interventions improve adherence.

Population

1,055 ambulatory patients dispensed amiodarone for at least 180 days across 10 health maintenance organizations (HMOs)

Intervention

Amiodarone therapy (dispensed for at least 180 days)

Outcome

Proportion of ambulatory patients who had liver aminotransferase and thyroid function tests during amiodarone therapy

Approximately half of ambulatory patients prescribed amiodarone do not receive the recommended concurrent monitoring for liver and thyroid toxicity.

Raebel et al. (2006) studied this question.

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Amiodarone monitoring gaps persist in ambulatory practice; this Level 3 cohort analysis leaves open whether targeted interventions improve adherence.