What question did this study set out to answer?

Assess the frequency, presentation, and clinical characteristics of central nervous system embolization in patients with pathologically verified atrial myxoma.

August 1, 1980Archives of Neurology

CNS Embolism due to Atrial Myxoma

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Population

40 patients with pathologically verified atrial myxoma identified between 1957 and 1977, age range 17 to 77…

Design

Case_series

Authors

BSBurton A. SandokMayo Clinic in Arizona

Discussion

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Implication

Supports embolization risk awareness in left atrial myxoma; case-level data leave optimal screening open.

Key Points

Assess the frequency, presentation, and clinical characteristics of central nervous system embolization in patients with pathologically verified atrial myxoma.
Retrospective analysis of 40 patients (aged 17–77 years, female-to-male ratio 3:1) with pathologically confirmed atrial myxoma between 1957 and 1977.
Evaluation of tumor location across left atrial (n=35), right atrial (n=3), bilateral (n=1), and sequential right-then-left atrial (n=1) presentations.
Ten of 37 patients (27%) with left atrial myxoma experienced at least one ischemic event secondary to embolization, affecting the cerebral hemispheres, brainstem, cerebellum, retina, and spinal cord.
Cardiac and constitutional symptoms predominated overall clinical presentations, although initial evaluation in some patients was driven primarily by neurologic deficits.

Structured PICO

Population

40 patients with pathologically verified atrial myxoma identified between 1957 and 1977, age range 17 to 77 years, with a 3:1 female predominance.

Outcome

Neurologic events suggesting ischemia secondary to embolizationhard clinical

Left atrial myxomas are associated with a high rate (27%) of central nervous system embolization, emphasizing the need for early clinical diagnosis using echocardiography.

Cite This Study

Burton A. Sandok (1980) studied this question.

synapsesocial.com/papers/6a7cb8f20d1c97f421a8b535 https://doi.org/10.1001/archneur.1980.00500570033004

Topics

Echocardiography

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CNS Embolism due to Atrial Myxoma

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

CNS Embolism due to Atrial Myxoma

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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