What question did this study set out to answer?

To determine the incidence, onset timeline, and mortality rates of adult respiratory distress syndrome among patients presenting with single versus multiple predispositions.

May 1, 1983Annals of Internal Medicine

Adult Respiratory Distress Syndrome: Risk with Common Predispositions

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Authors

AFAlpha A. FowlerJohns Hopkins University

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Implication

Multicenter survey reveals increased adult respiratory distress syndrome risk in predisposed hospital patients, indicating rapid progression and high mortality.

Key Points

To determine the incidence, onset timeline, and mortality rates of adult respiratory distress syndrome among patients presenting with single versus multiple predispositions.
Conducted a one-year survey across three hospitals identifying 993 predisposed individuals (936 with a single predisposition and 57 with multiple predispositions) alongside 20 additional cases from other causes (N=88 total syndrome cases).
Monitored patients for the development of respiratory distress syndrome, time to intubation and mechanical ventilation, and overall case fatality.
The incidence of the syndrome was significantly higher in patients with multiple predispositions compared to those with a single predisposition (24.6 vs. 5.8 per 100 patients, p < 0.0001).
Within 72 hours of predisposition onset, 89.5% of patients who developed the syndrome were intubated and placed on mechanical ventilation.
Overall mortality was 64.8% (57 of 88 patients died), with 90% of deaths occurring by day 14, showing no age- or sex-specific differences in incidence or mortality.

Cite This Study

Alpha A. Fowler (1983) studied this question.

synapsesocial.com/papers/6a7cbdad0d1c97f421a8b5fa https://doi.org/10.7326/0003-4819-98-5-593

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May 1, 1983Annals of Internal Medicine

Adult Respiratory Distress Syndrome: Risk with Common Predispositions

View Full Paper

Ask AI

Bookmark

Authors

AFAlpha A. FowlerJohns Hopkins University

Discussion

Member takes

Implication

Multicenter survey reveals increased adult respiratory distress syndrome risk in predisposed hospital patients, indicating rapid progression and high mortality.

Key Points

To determine the incidence, onset timeline, and mortality rates of adult respiratory distress syndrome among patients presenting with single versus multiple predispositions.
Conducted a one-year survey across three hospitals identifying 993 predisposed individuals (936 with a single predisposition and 57 with multiple predispositions) alongside 20 additional cases from other causes (N=88 total syndrome cases).
Monitored patients for the development of respiratory distress syndrome, time to intubation and mechanical ventilation, and overall case fatality.
The incidence of the syndrome was significantly higher in patients with multiple predispositions compared to those with a single predisposition (24.6 vs. 5.8 per 100 patients, p < 0.0001).
Within 72 hours of predisposition onset, 89.5% of patients who developed the syndrome were intubated and placed on mechanical ventilation.
Overall mortality was 64.8% (57 of 88 patients died), with 90% of deaths occurring by day 14, showing no age- or sex-specific differences in incidence or mortality.

Cite This Study

Alpha A. Fowler (1983) studied this question.

synapsesocial.com/papers/6a7cbdad0d1c97f421a8b5fa https://doi.org/10.7326/0003-4819-98-5-593

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