Why the study?
Does coronary thrombus composition differ between lysis-resistant and lysis-sensitive STEMI patients?
Does coronary thrombus composition differ between lysis-resistant and lysis-sensitive STEMI patients?
Coronary thrombi in STEMI patients resistant to fibrinolysis are characterized by higher fibrin, P-selectin, and VWF content, which may serve as predictors of thrombolysis resistance.
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May identify biomarkers for fibrinolysis resistance in STEMI; hypothesis-generating and requires prospective validation before clinical use.
Blanco et al. (2016) studied this question.
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