Population
Cats and humans (specifically human foot mentioned)
Comparison
Increased transmural pressure vs Normal/supine posture
Design
Other
Authors
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Highlights protective adaptation against dependent edema; leaves open its role in clinical edema syndromes.
Active vascular adaptation to hydrostatic load, primarily through reduction of capillary surface area, is the main mechanism preventing edema formation in dependent regions during quiet standing.
Mellander et al. (1964) studied this question.
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