Why the study?
Does nesiritide improve symptoms and diuresis in a patient with acute decompensated heart failure unresponsive to initial intravenous diuretics?
Does nesiritide improve symptoms and diuresis in a patient with acute decompensated heart failure unresponsive to initial intravenous diuretics?
In a case of acute decompensated heart failure unresponsive to initial intravenous diuretics, the addition of a nesiritide infusion resulted in significant diuresis and rapid symptom improvement.
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May support nesiritide in select diuretic-refractory ADHF; hypothesis-generating and requires randomized confirmation.
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D Fontana (2006) studied this question.
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