Why the study?
Randomized controlled trials evaluating the effectiveness, safety, cost-effectiveness, and user demand for online anticoagulation management are lacking.
Does warfarin management via a mobile app improve Time in Therapeutic Range (TTR) and cost-effectiveness compared to offline pharmacist-led management in patients post-cardiac valve replacement?
Population
405 patients post-cardiac valve replacement on warfarin therapy for at least 3 months
Comparison
Alfalfa mobile app warfarin management vs offline pharmacist-led outpatient clinic visits
Design
Randomized controlled trial
Follow-up
3 months
Authors
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Supports app-based warfarin management post-CVR; confirms higher TTR, safety, and cost-effectiveness versus traditional care in RCT.
Does warfarin management via a mobile app improve Time in Therapeutic Range (TTR) and cost-effectiveness compared to offline pharmacist-led management in patients post-cardiac valve replacement?
Mobile app-based warfarin management significantly improves Time in Therapeutic Range and cost-effectiveness compared to traditional outpatient clinics in post-cardiac valve replacement patients, though it may slightly increase minor bleeding.
Chen et al. (2025) studied this question.