Highlights acute perimyocarditis as a rare but potentially serious side effect of the mRNA-1273 SARS-CoV-2 vaccine.
Perimyocarditis may follow mRNA-1273 vaccination in young men; single case leaves open incidence and causality.
Myocarditis has been described previously as a rare side effect of both influenza and smallpox vaccines. In this report, we present a case of acute perimyocarditis in a young, healthy man after vaccination with the mRNA-1273 severe acute respiratory syndrome coronavirus -2 (SARS-CoV-2; Moderna) vaccine. He presented with chest pain and decompensated heart failure 3 days after administration of his second dose, and his symptoms resolved by 9 days post-inoculation. This case highlights a rare but potentially serious side effect of this mRNA vaccine that primary care physicians and cardiologists should be aware of in order to identify and appropriately manage these patients.
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Williams et al. (2021) studied this question.
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