Predictors and Long‐Term Clinical Impact of Acute Stent Malapposition: An Assessment of Dual Antiplatelet Therapy With Drug‐Eluting Stents (ADAPT‐DES) Intravascular Ultrasound Substudy
Why the study?
Does acute stent malapposition increase the risk of adverse clinical events in patients undergoing PCI with drug-eluting stents?
Population
2,072 patients with 2,446 culprit lesions undergoing percutaneous coronary intervention using drug-eluting…
Comparison
Presence of acute stent malapposition (ASM) vs Absence of acute stent malapposition (ASM)
Design
Cohort
Follow-up
2 years
Authors
Discussion
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Member takes
Implication
Acute stent malapposition may not elevate 2-year events after DES; leaves open need for randomized data before changing IVUS-guided practice.
Structured PICO
Does acute stent malapposition increase the risk of adverse clinical events in patients undergoing PCI with drug-eluting stents?
P
Population
2,072 patients with 2,446 culprit lesions undergoing percutaneous coronary intervention using drug-eluting stents with post-PCI intravascular ultrasound
I
Intervention
Presence of acute stent malapposition (ASM)
C
Comparator
Absence of acute stent malapposition (ASM)
O
Outcome
Incidence of cardiac death, myocardial infarction, stent thrombosis (early, late, or very late), or clinically driven target lesion revascularization at 2-year follow-uphard clinical
Acute stent malapposition detected by IVUS after drug-eluting stent implantation does not predict adverse long-term clinical outcomes, including stent thrombosis, at 2 years.
Cite This Study
Wang et al. (2016) studied this question.