What question did this study set out to answer?

To evaluate the safety and clinical effectiveness of percutaneous stellate ganglion block in patients experiencing an electrical storm refractory to standard therapies.

January 30, 2024European Heart JournalOpen Access

Electrical storm treatment by percutaneous stellate ganglion block: the STAR study

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Why the study?

Electrical storm has few established treatment options, and prospective multicentre evidence regarding the safety and effectiveness of percutaneous stellate ganglion block was lacking.

Does percutaneous stellate ganglion block reduce treated arrhythmic events in patients with refractory electrical storm?

Population

131 patients with electrical storm refractory to standard treatment across 19 centres

Comparison

12 h following PSGB vs 12 h before the procedure

Design

Multicentre observational study

Follow-up

12 h

Authors

SSSimone SavastanoPoliclinico San Matteo Fondazione EBEnrico BaldiPoliclinico San Matteo Fondazione SCSara CompagnoniUniversity of Pavia

Discussion

Member takes

Implication

May support PSGB in refractory electrical storm; leaves open need for randomized confirmation.

Key Points

To evaluate the safety and clinical effectiveness of percutaneous stellate ganglion block in patients experiencing an electrical storm refractory to standard therapies.
Multicenter prospective observational study of 131 patients suffering from refractory electrical storm enrolled across 19 centers between July 2017 and June 2023.
Patients underwent a total of 184 percutaneous stellate ganglion block procedures performed using either an anterior anatomical or a lateral ultrasound-guided approach.
The primary endpoint was a reduction of treated arrhythmic episodes by at least 50% comparing the 12 hours after the procedure with the 12 hours prior.
The primary outcome was achieved in 92% of patients, with a median reduction in treated arrhythmic episodes of 100% (interquartile range, -100% to -92.3%).
Treated arrhythmic episodes decreased from 6 (3–15.8) in the 12 hours before the first procedure to 0 (0–1) in the 12 hours after the last procedure (P < .0001), and from 2 (0–6) to 0 (0–0) comparing 1 hour before and after each procedure (P < .001).
Major procedural complications occurred in 1 of 184 procedures (0.5%).

Structured PICO

Does percutaneous stellate ganglion block reduce treated arrhythmic events in patients with refractory electrical storm?

Population

131 patients suffering from an electrical storm (ES) refractory to standard treatment, median age 68, 83.2% male, with depressed left ventricular ejection fraction (25.0 ± 12.3%).

Intervention

Percutaneous stellate ganglion block (PSGB) using anterior anatomical or lateral ultrasound-guided approach

Outcome

Reduction of treated arrhythmic events by at least 50% comparing the 12 h following PSGB with the 12 h before the procedure

Percutaneous stellate ganglion block is highly effective and safe for acutely reducing arrhythmic events in patients with refractory electrical storm.

Cite This Study

Savastano et al. (2024) studied this question.

synapsesocial.com/papers/6a7cd77e37b87b49edee241d https://doi.org/10.1093/eurheartj/ehae021

Topics

Ventricular arrhythmias

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Electrical storm treatment by percutaneous stellate ganglion block: the STAR study

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Electrical storm treatment by percutaneous stellate ganglion block: the STAR study

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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