Why the study?
Do endothelial NO synthase gene polymorphisms affect the long-term cumulative burden and trend of blood pressure since childhood?
Do endothelial NO synthase gene polymorphisms affect the long-term cumulative burden and trend of blood pressure since childhood?
Endothelial NO synthase gene polymorphisms influence the long-term burden and trend of blood pressure since childhood in females, potentially contributing to their predisposition to hypertension.
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May inform sex-specific BP risk in females; hypothesis-generating and requires replication before any clinical consideration.
Chen et al. (2004) studied this question.
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