Why the study?
Does hypertension increase aortic root size and the prevalence of aortic regurgitation in healthy, asymptomatic individuals?
Population
220 healthy, asymptomatic men and women, comprising 110 hypertensive and 110 normotensive subjects matched…
Comparison
Hypertension vs Normotension
Design
Cross-sectional
Authors
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Hypertension-associated proximal aortic enlargement warrants cautious surveillance in asymptomatic adults; leaves open progression to regurgitation or events.
Does hypertension increase aortic root size and the prevalence of aortic regurgitation in healthy, asymptomatic individuals?
Hypertension is associated with a slight increase in proximal ascending aorta and supra-aortic ridge size, but does not appear to increase the prevalence of aortic regurgitation in asymptomatic individuals.
Roman et al. (1996) studied this question.
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