Why the study?
Simplifying assumptions and proxy measures compromise data-driven disease modeling, leaving gaps in knowledge regarding the duration of the infectious period of FMDV in pigs and its viability in decaying carcasses.
Population
Sentinel and donor pigs infected with FMDV A24 Cruzeiro and carcasses stored at 4oC
Comparison
Serial exposure across post-infection timepoints and tissue viability across post-mortem intervals
Design
Prospective experimental transmission and tissue-viability study
Follow-up
11 weeks post mortem
Authors
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New FMDV infectious period data may refine pig outbreak models; leaves open validation in field settings before broader use.
FMDV-infected pigs can transmit the virus up to 10 days post-infection, and the virus remains viable in carcass vesicle epithelium for at least 11 weeks, providing critical parameters for outbreak modeling.
Stenfeldt et al. (2020) studied this question.
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