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September 21, 2018EP Europace

Cryoballoon vs. radiofrequency ablation for atrial fibrillation: a study of outcome and safety based on the ESC-EHRA atrial fibrillation ablation long-term registry and the Swedish catheter ablation registry

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Why the study?

Does second-generation cryoballoon ablation reduce repeat AF ablation compared to irrigated radiofrequency ablation in patients undergoing their first AF ablation?

Population

4,657 patients undergoing their first atrial fibrillation ablation from the Swedish catheter ablation…

Comparison

Second-generation cryoballoon ablation (CRYO) vs Irrigated radiofrequency (RF) energy ablation

Design

Cohort

Follow-up

12 months

Authors

DMDavid MörtsellEAElena ArbeloNDNikolaos Dagres

Discussion

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Overview

May favor cryoballoon for fewer re-ablations in first AF ablation; hypothesis-generating and requires randomized confirmation.

Structured PICO

Does second-generation cryoballoon ablation reduce repeat AF ablation compared to irrigated radiofrequency ablation in patients undergoing their first AF ablation?

P
Population
4,657 patients undergoing their first atrial fibrillation (AF) ablation from the Swedish catheter ablation registry and the ESC-EHRA Atrial Fibrillation Ablation Long-Term registry
I
Intervention
Second-generation cryoballoon ablation (CRYO)
C
Comparator
Irrigated radiofrequency (RF) energy ablation
O
Outcome
Repeat AF ablationhard clinical

Cryoballoon ablation for first-time AF ablation is associated with lower re-ablation rates and shorter procedure times compared to radiofrequency ablation, with similar safety profiles.

Limitations

  • Recognized limitations with registries

Cite This Study

Mörtsell et al. (2018) studied this question.

synapsesocial.com/papers/6a7cda660594c5b5d191ae11https://doi.org/10.1093/europace/euy239
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