Why the study?
Does intensive blood-pressure control (target <120 mm Hg) reduce death compared to standard control (target <140 mm Hg)?
Population
Patients in the SPRINT trial (appropriate population for blood-pressure targets)
Comparison
Intensive blood-pressure control vs Standard blood-pressure control
Design
Editorial, Randomly assigned
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This letter highlights a potential confounding factor in the SPRINT trial regarding the nonstandard withdrawal of antihypertensive therapy in the standard-treatment group.
Does intensive blood-pressure control (target <120 mm Hg) reduce death compared to standard control (target <140 mm Hg)?
This letter highlights a potential confounding factor in the SPRINT trial regarding the nonstandard withdrawal of antihypertensive therapy in the standard-treatment group.
A 2016 study studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: