November 1, 2004The Canadian Journal of Psychiatry
Characterizing Coronary Heart Disease Risk in Chronic Schizophrenia: High Prevalence of the Metabolic Syndrome
Why the study?
What is the prevalence of coronary heart disease risk factors and metabolic syndrome in patients with chronic schizophrenia compared to the general population?
Population
240 patients with chronic schizophrenia or schizoaffective disorder
Design
Cross-sectional
Authors
Discussion
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Implication
May warrant enhanced CHD screening in schizophrenia; extends cross-sectional prevalence data but leaves interventional questions open.
Structured PICO
What is the prevalence of coronary heart disease risk factors and metabolic syndrome in patients with chronic schizophrenia compared to the general population?
P
Population
240 patients with chronic schizophrenia or schizoaffective disorder
C
Comparator
Large national sample (Canadian Heart Health Survey) matched for age and sex, and US adult population
O
Outcome
Prevalence and characteristics of coronary heart disease (CHD) risk factors, Framingham 10-year risk of myocardial infarction, and rates of metabolic syndromesurrogate
Patients with chronic schizophrenia have a significantly higher prevalence of metabolic syndrome and elevated 10-year CHD risk compared to the general population, underscoring the need for cardiovascular screening.
Cite This Study
Cohn et al. (2004) studied this question.