Why the study?
Are serum uric acid concentrations within the physiological range associated with impaired endothelial function and increased atherosclerosis in healthy adults?
Population
124 healthy volunteers between 26 and 55 years of age with serum uric acid levels in the normal…
Design
Cross-sectional
Authors
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Should not yet change practice in healthy adults; hypothesis-generating for uric acid's role in early atherosclerosis.
Are serum uric acid concentrations within the physiological range associated with impaired endothelial function and increased atherosclerosis in healthy adults?
Even within the physiological range, higher serum uric acid levels are associated with early markers of atherosclerosis and endothelial dysfunction in healthy adults.
Erdoğan et al. (2005) studied this question.
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