Key Points
- To review the clinical assessment, diagnostic classification, and prognostic significance of myocardial injury and type 2 myocardial infarction in clinical practice.
- Reviewed the universal definition distinguishing type 1 myocardial infarction (plaque rupture), type 2 myocardial infarction (oxygen supply-demand imbalance), and non-ischaemic myocardial injury.
- Evaluated diagnostic implementation challenges, prevalence, and prognostic outcomes among hospitalized patient cohorts.
- Myocardial injury and type 2 myocardial infarction occur in more than one-third of all hospitalized patients.
- Patients with these diagnoses experience poor short- and long-term outcomes, with two-thirds dying within 5 years.
- Identifying underlying coronary artery disease in type 2 myocardial infarction allows targeted secondary prevention to improve patient outcomes.
Structured PICO
PPopulationPatients with myocardial injury and infarction in clinical practice
Clinicians should consider whether coronary artery disease contributes to myocardial injury or type 2 myocardial infarction to target secondary prevention and improve outcomes.