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May 1, 2003Expert Review of Cardiovascular Therapy

The role of renin–angiotensin– aldosterone system inhibition in chronic kidney disease

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Why the study?

Does renin-angiotensin-aldosterone system inhibition improve renal and cardiovascular outcomes in patients with chronic kidney disease?

Population

Patients with chronic kidney disease (CKD)

Design

Review

Authors

KNKeith C. NorrisPennington Biomedical Research CenterCVCharles M. VaughnWestern University of Health Sciences

Discussion

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Implication

Supports RAAS inhibition in CKD for renal/CV protection; leaves open optimal combinations and dosing in advanced stages.

Structured PICO

Does renin-angiotensin-aldosterone system inhibition improve renal and cardiovascular outcomes in patients with chronic kidney disease?

P
Population
Patients with chronic kidney disease (CKD)
I
Intervention
Renin-angiotensin-aldosterone system (RAAS) inhibition (ACEIs and ARBs)
O
Outcome
Progression of CKD and adverse cardiovascular events

RAAS inhibition with ACEIs and ARBs provides significant renal and cardioprotection in patients with chronic kidney disease.

Cite This Study

Norris et al. (2003) studied this question.

synapsesocial.com/papers/6a7cdebde54b2084843e15eahttps://doi.org/10.1586/14779072.1.1.51
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Also Consider

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