Key result
Severe mental illness linked to ~57% higher odds of cardiovascular disease.
Why the study?
Does severe mental illness increase the risk of cardiovascular disease in people of African ancestry?
Population
2305 participants of African ancestry from the African Ancestry-Genomic Psychiatric Cohort enrolled in…
Comparison
Severe mental illness including schizophrenia… vs Participants without severe mental illness
Design
Cohort
Authors
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Severe mental illness is independently associated with a significantly higher risk of cardiovascular disease among Black Americans, highlighting the need for targeted clinical and lifestyle interventions.
Cohort (n=2,305)
No
Does severe mental illness increase the risk of cardiovascular disease in people of African ancestry?
Odds Ratio: 1.57 (95% CI 1.14–2.15)
Severe mental illness is independently associated with a significantly higher risk of cardiovascular disease among Black Americans, highlighting the need for targeted clinical and lifestyle interventions.
Salisu et al. (2025) conducted a cohort in Severe mental illness and cardiovascular disease (n=2,305). Severe mental illness (SMI) vs. Participants without SMI was evaluated on Cardiovascular disease (CVD) (OR 1.57, 95% CI 1.14-2.15). Severe mental illness was independently associated with 57% higher odds of cardiovascular disease (OR 1.57; 95% CI 1.14-2.15) compared to those without severe mental illness.
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