Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 4, 2023European Heart JournalOpen Access

Lifelong endurance exercise and its relation with coronary atherosclerosis

View Full Paper
Ask AI
Bookmark
Share

Why the study?

The impact of long-term endurance sport participation on coronary atherosclerosis and acute cardiac events remains controversial.

Does lifelong endurance sport participation reduce the prevalence of coronary atherosclerosis in healthy males with a low cardiovascular risk profile?

Population

191 lifelong master endurance athletes, 191 late-onset athletes, and 176 healthy non-athletes, all male

Comparison

Lifelong master endurance athletes vs late-onset athletes vs healthy non-athletes

Design

Prospective observational cohort study

Authors

RBRuben De BosscherCDChristophe DausinPCPiet Claus

Discussion

Loading...

Member takes

Overview

Higher plaque burden in lifelong athletes warrants caution in risk assessment; leaves open whether this increases events in low-risk masters.

Structured PICO

Does lifelong endurance sport participation reduce the prevalence of coronary atherosclerosis in healthy males with a low cardiovascular risk profile?

P
Population
558 males with a low cardiovascular risk profile, comprising 191 lifelong master endurance athletes, 191 late-onset athletes (endurance sports initiation after 30 years of age), and 176 healthy non-athletes, median age 55.
I
Intervention
Lifelong endurance sport participation and late-onset endurance sport participation
C
Comparator
Healthy non-athletic lifestyle (healthy non-athletes)
O
Outcome
Prevalence of coronary plaques (calcified, mixed, and non-calcified) on computed tomography coronary angiographysurrogate

Lifelong endurance sport participation in healthy men is paradoxically associated with a higher prevalence of coronary plaques, including non-calcified proximal plaques, compared to a healthy non-athletic lifestyle.

Limitations

  • Lack of longitudinal data on cardiovascular events to reconcile with imaging findings

Cite This Study

Bosscher et al. (2023) studied this question.

synapsesocial.com/papers/6a7ce4cba0d4e77c65aeb369https://doi.org/10.1093/eurheartj/ehad152
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endurance exercise and the risk of cardiovascular pathology in men: a comparison between lifelong and late-onset endurance training and a non-athletic lifestyle - rationale and design of the Master@Heart study, a prospective cohort trial2021 · 30 citations
  2. 2Longitudinal insights into coronary plaque amongst master athletes2024 · 1 citations
  3. 3Coronary Atherosclerosis in Master Athletes: Current Knowledge and Future Challenges2026
  4. 4Resilience against exercise-related coronary atherosclerosis: A case study in a master athlete participating in 500 marathons2025
  5. 5215 Longitudinal study of plaque morphology in masters athletes2024 · 1 citations