November 21, 2013Psychological Medicine
Metabolic syndrome and metabolic abnormalities in patients with major depressive disorder: a meta-analysis of prevalences and moderating variables
Why the study?
Is major depressive disorder associated with an increased prevalence of metabolic syndrome compared to matched controls?
Population
18 studies pooling 5,531 individuals with interview-defined major depressive disorder, mean age 45.5 years…
Comparison
Major depressive disorder (exposure) vs Age- and gender-matched control groups
Design
Meta-analysis
Authors
Discussion
Loading...
Member takes
Overview
Supports MetS screening in MDD patients; confirms association and extends cardiometabolic comorbidity research.
Structured PICO
Is major depressive disorder associated with an increased prevalence of metabolic syndrome compared to matched controls?
P
Population
18 studies pooling 5,531 individuals with interview-defined major depressive disorder (MDD), mean age 45.5 years, 38.9% male.
I
Intervention
Major depressive disorder (exposure)
C
Comparator
Age- and gender-matched control groups
O
Outcome
Prevalence of metabolic syndrome (MetS) using any standardized criteriasurrogate
Patients with major depressive disorder have a significantly higher prevalence of metabolic syndrome, particularly those prescribed antipsychotics, highlighting them as a high-risk group for cardiovascular morbidity.
Cite This Study
Vancampfort et al. (2013) studied this question.